Search on:
PROTO-ONCOGENE PROTEINS C-MET
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Proto-Oncogene Proteins c-met
Descriptor
Spanish
:
Proteínas Proto-Oncogénicas c-met
Descriptor
Portuguese
:
Proteínas Proto-Oncogênicas c-met
Synonyms
English
:
HGF Receptor
Hepatocyte Growth Factor Receptor
c-met Proteins
met Proto-Oncogene Proteins
Tree Number:
D08.811.913.696.620.682.725.400.075
D12.776.543.750.060.186
D12.776.543.750.750.400.100
D12.776.624.664.700.186
Definition
English
:
Cell surface protein-tyrosine kinase receptors for
HEPATOCYTE GROWTH FACTOR
. They consists of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the
catalytic domain
and sites critical for the regulation of kinase activity. Mutations of the gene for
PROTO-ONCOGENE PROTEINS C-MET
are associated with papillary renal
carcinoma
and other neoplasia.
Indexing Annotation
English
:
DF: C MET
PROTEINS
History Note
English
:
2006, 1998-1999
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
33476
Unique Identifier:
D019859
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS